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I highly recommend making this your go-to clinic.", "reviewRating": { "@type": "Rating", "ratingValue": "5", "bestRating": "5", "worstRating": "1" } } }, { "@type": "BlogPosting", "@id": "/trt-and-sleep-apnoea/#blogposting", "mainEntityOfPage": { "@type": "WebPage", "@id": "/trt-and-sleep-apnoea/" }, "headline": "TRT and Sleep Apnoea: Understanding the Connection", "datePublished": " T00:00:00+00:00", "dateModified": " T00:00:00+00:00", "author": { "@type": "Person", "name": "Omniya Clinic", "url": "/" }, "publisher": { "@type": "Organization", "name": "Omniya Clinic", "logo": { "@type": "ImageObject", "url": "/wp-content/uploads/2024/01/Omniya-Logo-Vector-Gold-BD9964.png" } }, "description": "Omniya Clinic examines the intricate relationship between Testosterone Replacement Therapy (TRT) and obstructive sleep apnoea (OSA), highlighting the benefits and risks.", "image": { "@type": "ImageObject", "url": "/wp-content/uploads/2024/01/tiredness-trt-hrt-iv-drip-omniya-clinic-1200x801.jpg.webp", "width": 1200, "height": } }, { "@type": "ReserveAction", "target": { "@type": "EntryPoint", "urlTemplate": "/book-an-appointment/", "inLanguage": "en-GB", "actionPlatform": "/MobileWebPlatform" }, "result": { "@type": "Reservation", "name": "TRT and Sleep Apnoea Consultation Booking" } } ]<br>}<br><br><br><br>{ "@context": "", "@type": "FAQPage", "mainEntity": [{ "@type": "Question", "name": "Can TRT Cause Sleep Apnoea?", "acceptedAnswer": { "@type": "Answer", "text": "Research suggests that in some men, TRT may worsen or contribute to sleep apnoea symptoms, especially in those already predisposed to the condition. The exact mechanism by which this may occur remains unclear. One theory is that testosterone may affect the dilation and contraction of the airways; as testosterone levels fluctuate (particularly in patients using certain injectable formulations) so too does the degree of airway obstruction. A major confounding factor is that the primary risk factor for OSA is being overweight, and the study did not take into account the BMI/body fat of the patients enrolled, nor those of the control group. Nonetheless, if you have sleep apnoea or suspect you might, it’s crucial to discuss this with the specialists at Omniya Clinic before starting TRT.<br>According to a study published in the Journal of Clinical Endocrinology & Metabolism, sleep apnoea disrupts the normal sleep cycle, which is critical for testosterone production. The majority of testosterone is produced during REM (rapid eye movement) sleep, which is frequently interrupted in individuals with sleep apnoea. This reduction in testosterone production can lead to a range of symptoms such as fatigue, reduced libido, and muscle loss, which are also common in individuals with low-T. Studies looking at testosterone levels in patients with OSA have not however found that testosterone levels recover once the OSA is treated." } }, { "@type": "Question", "name": "How does TRT affect OSA?", "acceptedAnswer": { "@type": "Answer", "text": "A study published in The American Journal of Respiratory and Critical Care Medicine found that TRT can potentially worsen obstructive sleep apnoea by increasing the number of apnoea episodes during sleep. The exact mechanisms are not entirely understood. The studies that have shown this correlation have either been small studies or a larger study with a significant confounding factor. We do know that one of the risks of TRT is that it can cause the blood count to rise, also known as polycythaemia. This is also a complication of OSA. Thus, patients with OSA starting TRT are at a greater risk of polycythaemia.<br><br>Whilst the research that looks to clarify the relationship between TRT and OSA is inconclusive and more large scale, robust studies will need to be conducted to further delineate this, it is widely agreed that TRT should be prescribed with caution in individuals with untreated sleep apnoea. If there is a suspicion of OSA, some doctors may ask for a sleep study to confirm the diagnosis and subsequent treatment of OSA with use of CPAP therapy at night, before starting TRT. 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